Tenecteplase is here: Navigating the shift of a stroke thrombolytic in the United States prior to FDA approval: a mini-review on rationale, barriers and pathways
Julian M. Burwell, Jason R. Howay, Lisa Wasko, Samantha Doucoure, Jamie L. Kerestes, Clemens M. Schirmer, David Ermak, Anthony Noto, Philipp Hendrix
Until March 2025, alteplase (TPA) was the sole thrombolytic agent approved by the U.S. Food and Drug Administration (FDA) for the treatment of acute ischemic stroke (AIS)